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Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure

Treatment of decompensated heart failure often includes administration of levosimendan. Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and mediates dysregulation of vascular tone in heart failure. We evaluated the effects of levosimendan-treatment on MPO i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Adam, Matti, Meyer, Sven, Knors, Henning, Klinke, Anna, Radunski, Ulf K., Rudolph, Tanja K., Rudolph, Volker, Spin, Joshua M., Tsao, Philip S., Costard-Jäckle, Angelika, Baldus, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394753/
https://ncbi.nlm.nih.gov/pubmed/25867530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09704
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