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Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1

Genetic variants of human N-acetyltransferase 1 (NAT1) are associated with cancer and birth defects. N- and O-acetyltransferase catalytic activities, Michaelis-Menten kinetic constants (Km & Vmax), and steady state expression levels of NAT1-specific mRNA and protein were determined for the refer...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhu, Yuanqi, Hein, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575040/
https://ncbi.nlm.nih.gov/pubmed/17909564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.tpj.6500483
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