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Functional Effects of Genetic Polymorphisms in the N-acetyltransferase 1 Coding and 3′ Untranslated Regions

BACKGROUND: The functional effects of N-acetyltransferase 1 (NAT1) polymorphisms and haplotypes are poorly understood, compromising the validity of associations reported with diseases including birth defects and numerous cancers. METHODS: We investigated the effects of genetic polymorphisms within t...

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Detalhes bibliográficos
Main Authors: Zhu, Yuanqi, States, J. Christopher, Wang, Yang, Hein, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252750/
https://ncbi.nlm.nih.gov/pubmed/21290563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20763
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