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STRUCTURE-FUNCTION ANALYSES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN HUMAN N-ACETYLTRANSFERASE 1

Human N-acetyltransferase 1 (NAT1) alleles are characterized by one or more single nucleotide polymorphisms (SNPs) associated with rapid and slow acetylation phenotypes. NAT1 both activates and deactivates arylamine drugs and carcinogens, and NAT1 polymorphisms are associated with increased frequenc...

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Detalhes bibliográficos
Main Authors: Walraven, Jason M., Trent, John O., Hein, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265210/
https://ncbi.nlm.nih.gov/pubmed/18259988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602530701852917
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