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Structure/Function Evaluations of Single Nucleotide Polymorphisms in Human N-Acetyltransferase 2

Arylamine N-acetyltransferase 2 (NAT2) modifies drug efficacy/toxicity and cancer risk due to its role in bioactivation and detoxification of arylamine and hydrazine drugs and carcinogens. Human NAT2 alleles possess a combination of single nucleotide polymorphisms (SNPs) associated with slow acetyla...

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Detalhes bibliográficos
Main Authors: Walraven, Jason M., Zang, Yu, Trent, John O., Hein, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507886/
https://ncbi.nlm.nih.gov/pubmed/18680467
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