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STRUCTURE-FUNCTION ANALYSES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN HUMAN N-ACETYLTRANSFERASE 1

Human N-acetyltransferase 1 (NAT1) alleles are characterized by one or more single nucleotide polymorphisms (SNPs) associated with rapid and slow acetylation phenotypes. NAT1 both activates and deactivates arylamine drugs and carcinogens, and NAT1 polymorphisms are associated with increased frequenc...

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Hlavní autoři: Walraven, Jason M., Trent, John O., Hein, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265210/
https://ncbi.nlm.nih.gov/pubmed/18259988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602530701852917
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