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Recombinant Bovine Dihydrofolate Reductase Produced by Mutagenesis and Nested PCR of Murine Dihydrofolate Reductase cDNA

Recent reports of the slow-tight binding inhibition of bovine liver dihydrofolate reductase (bDHFR) in the presence of polyphenols isolated from green tea leaves has spurred renewed interest in the biochemical properties of bDHFR. Earlier studies were done with native bDHFR but in order to validate...

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Autores principales: Cody, Vivian, Mao, Qilong, Queener, Sherry F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575037/
https://ncbi.nlm.nih.gov/pubmed/18672067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2008.07.001
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