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Relationship of cytochrome P450 pharmacogenetics to the effects of yohimbine on gastrointestinal transit and catecholamines in healthy subjects
Alpha-2 adrenergic receptors tonically inhibit colonic motility and the α(2)-adrenergic antagonist yohimbine, given intravenously, increased colonic tone in humans. However, the effect of yohimbine on colonic transit in humans is unknown. In this study, 30 healthy volunteers were randomized to yohim...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574973/ https://ncbi.nlm.nih.gov/pubmed/18433425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2008.01124.x |
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