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Effects of glucagon-like peptide-1, yohimbine, and nitrergic modulation on sympathetic and parasympathetic activity in humans

Glucagon-like peptide-1 (GLP-1), an incretin, which is used to treat diabetes mellitus in humans, inhibited vagal activity and activated nitrergic pathways. In rats, GLP-1 also increased sympathetic activity, heart rate, and blood pressure (BP). However, the effects of GLP-1 on sympathetic activity...

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Detalhes bibliográficos
Main Authors: Bharucha, Adil E., Charkoudian, Nisha, Andrews, Christopher N., Camilleri, Michael, Sletten, David, Zinsmeister, Alan R., Low, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536850/
https://ncbi.nlm.nih.gov/pubmed/18596108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00153.2008
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