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PROTEASOME INHIBITORS INDUCE APOPTOSIS OF PROSTATE CANCER CELLS BY INDUCING NUCLEAR TRANSLOCATION OF IκBα

Proteasome inhibitors are known to suppress the proteasome-mediated degradation of IκBα in stimulated cells. This results in the cytoplasmic retention of NFκB and its reduced nuclear transcriptional activity. In this study, we show that in the metastatic prostate cancer cells, the proteasome inhibit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vu, Hai-Yen, Juvekar, Ashish, Ghosh, Chandra, Ramaswami, Sitharam, Le, Dung Hong, Vancurova, Ivana
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574911/
https://ncbi.nlm.nih.gov/pubmed/18468507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.04.026
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