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PROTEASOME INHIBITION BY BORTEZOMIB INCREASES IL-8 EXPRESSION IN ANDROGEN-INDEPENDENT PROSTATE CANCER CELLS: THE ROLE OF IKKα()
Expression of the pro-inflammatory and pro-angiogenic chemokine interleukin-8 (IL-8), which is regulated at the transcriptional level by NFκB, is constitutively increased in the androgen independent metastatic prostate cancer and correlates with poor prognosis. Inhibition of NFκB-dependent transcrip...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750091/ https://ncbi.nlm.nih.gov/pubmed/23894194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300895 |
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