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Gene-Specific Repression of Proinflammatory Cytokines in Stimulated Human Macrophages by Nuclear IκBα

We have previously shown that increased nuclear accumulation of IκBα inhibits NF-κB activity and induces apoptosis in human leukocytes. In this study, we wanted to explore the possibility that the nucleocytoplasmic distribution of IκBα can be used as a therapeutic target for the regulation of NF-κB–...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ghosh, Chandra C., Ramaswami, Sitharam, Juvekar, Ashish, Vu, Hai-Yen, Galdieri, Luciano, Davidson, Dennis, Vancurova, Ivana
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078650/
https://ncbi.nlm.nih.gov/pubmed/20696864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902230
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