Invasion suppressor cystatin E/M (CST6): High-level cell type-specific expression in normal brain and epigenetic silencing in gliomas

DNA hypermethylation mediated gene silencing is a frequent and early contributor to aberrant cell growth and invasion in cancer. Malignant gliomas are the most common primary brain tumors in adults and the second most common tumor in children. Morbidity and mortality are high in glioma patients beca...

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Bibliografiske detaljer
Main Authors: Qiu, Jingxin, Ai, Lingbao, Ramachandran, Cheppail, Yao, Bing, Gopalakrishnan, Suhasni, Fields, C. Robert, Delmas, Amber L., Dyer, Lisa M., Melnick, Steven J., Yachnis, Anthony T., Schwartz, Philip H., Fine, Howard A., Brown, Kevin D., Robertson, Keith D.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574902/
https://ncbi.nlm.nih.gov/pubmed/18607344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.66
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