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Array-Based Approaches for the Identification of Epigenetic Silenced Tumor Suppressor Genes

Carcinogenesis involves the inactivation or inhibition of genes that function as tumor suppressors. Deletions, mutations, or epigenetic silencing of tumor suppressor genes can lead to altered growth, differentiation, and apoptosis. DNA methylation and histone modifications are important epigenetic m...

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Detalles Bibliográficos
Main Authors: Takai, Noriyuki, Narahara, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado: Bentham Science Publishers Ltd. 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674306/
https://ncbi.nlm.nih.gov/pubmed/19424480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920208783884892
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