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Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanoma

The full molecular consequences of oncogene activation during tumorigenesis are not well understood, but several studies have recently linked oncogene activation to epigenetic silencing of specific genes.(1,2) Transcriptional repressor Id1 is overexpressed in many malignancies including melanoma, an...

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Autors principals: Healey, Megan A., Deaton, Staci L., Alder, Jonathan K., Winnepenninckx, Véronique, Casero, Robert A., Herman, James G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654680/
https://ncbi.nlm.nih.gov/pubmed/20484992
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