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Epigenetic silencing of tumor suppressor genes during in vitro Epstein–Barr virus infection
DNA-methylation at CpG islands is one of the prevalent epigenetic alterations regulating gene-expression patterns in mammalian cells. Hypo- or hypermethylation-mediated oncogene activation, or tumor suppressor gene (TSG) silencing mechanisms, widely contribute to the development of multiple human ca...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577197/ https://ncbi.nlm.nih.gov/pubmed/26324942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503806112 |
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