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TGFβ-induced FoxP3(+) Regulatory T Cells Rescue Scurfy Mice
Scurfy mice have a deletion in the forkhead domain of Foxp3, fail to develop thymic-derived Foxp3(+) regulatory T cells (nTreg), and develop a fatal lymphoproliferative syndrome with multi-organ inflammation. Transfer of thymic-derived Foxp3(+) nTreg into neonatal Scurfy mice prevents the developmen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574868/ https://ncbi.nlm.nih.gov/pubmed/18546144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838346 |
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