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Autoantibodies in Scurfy Mice and IPEX Patients Recognize Keratin 14
Scurfy mice have a deletion in the Foxp3 gene, resulting in a failure to generate Foxp3(+) regulatory T cells, and they subsequently develop severe CD4(+) T-cell-mediated autoimmune inflammation. Multiple organs are involved, but the skin is one of the main organs affected. During the course of dise...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767981/ https://ncbi.nlm.nih.gov/pubmed/20147963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.16 |
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