Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme

BACKGROUND: Regions of hypoxia within glioblastoma multiforme (GBM) tumors are common and may influence a tumor’s aggressiveness, response to treatment, and the patient’s overall survival. We examined four markers of hypoxia (HIF-1α, GLUT-1, VEGF, CA IX), cellular proliferation and microvascular den...

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Hauptverfasser: Flynn, Jeannette R., Wang, Libo, Gillespie, David L., Stoddard, Gregory J., Reid, Jason K., Owens, Jason, Ellsworth, Grant B., Salzman, Karen L., Kinney, Anita Y., Jensen, Randy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574798/
https://ncbi.nlm.nih.gov/pubmed/18618497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23678
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