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PREOPERATIVE DYNAMIC CONTRAST-ENHANCED MRI CORRELATES WITH MOLECULAR MARKERS OF HYPOXIA AND VASCULARITY IN SPECIFIC AREAS OF INTRATUMORAL MICROENVIRONMENT AND IS PREDICTIVE OF PATIENT OUTCOME

BACKGROUND: Measures of tumor vascularity and hypoxia have been correlated with glioma grade and outcome. Dynamic contrast-enhanced MRI (DCE-MRI) can noninvasively map multiple parameters of tumor hypoxia, blood flow, and vascularity. In this prospective observational cohort pilot study, our goal wa...

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Detalhes bibliográficos
Main Authors: Jensen, Randy, Salzman, Karen, Schabel, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144514/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.47
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