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Preoperative dynamic contrast-enhanced MRI correlates with molecular markers of hypoxia and vascularity in specific areas of intratumoral microenvironment and is predictive of patient outcome

BACKGROUND: Measures of tumor vascularity and hypoxia have been correlated with glioma grade and outcome. Dynamic contrast-enhanced (DCE) MRI can noninvasively map tumor blood flow, vascularity, and permeability. In this prospective observational cohort pilot study, preoperative imaging was correlat...

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Bibliografiske detaljer
Main Authors: Jensen, Randy L., Mumert, Michael L., Gillespie, David L., Kinney, Anita Y., Schabel, Matthias C., Salzman, Karen L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895375/
https://ncbi.nlm.nih.gov/pubmed/24305704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not148
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