Early Growth Response Gene-1 Regulates Hypoxia-Induced Expression of Tissue Factor in Glioblastoma Multiforme through Hypoxia-Inducible Factor-1–Independent Mechanisms

Hypoxia strongly up-regulates tissue factor and promotes plasma clotting by glioblastoma multiforme, but transcriptional mechanisms remain undefined. Here, we investigated the potential roles of early growth response gene-1 (Egr-1), Sp1, nuclear factor-κB (NF-κB), activator protein-1 (AP-1), and hyp...

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Detalhes bibliográficos
Main Authors: Rong, Yuan, Hu, Fang, Huang, RuoPan, Mackman, Nigel, Horowitz, Jonathan M., Jensen, Randy L., Durden, Donald L., Van Meir, Erwin G., Brat, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610484/
https://ncbi.nlm.nih.gov/pubmed/16849552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-0346
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