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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

Glioblastomas, like other solid tumors, have extensive areas of hypoxia and necrosis. The importance of hypoxia in driving tumor growth is receiving increased attention. Hypoxia-inducible factor 1 (HIF-1) is one of the master regulators that orchestrate the cellular responses to hypoxia. It is a het...

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Detalhes bibliográficos
Main Authors: Kaur, Balveen, Khwaja, Fatima W., Severson, Eric A., Matheny, Shannon L., Brat, Daniel J., Van Meir, Erwin G.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871894/
https://ncbi.nlm.nih.gov/pubmed/15831232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704001115
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