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Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

Glioblastomas, like other solid tumors, have extensive areas of hypoxia and necrosis. The importance of hypoxia in driving tumor growth is receiving increased attention. Hypoxia-inducible factor 1 (HIF-1) is one of the master regulators that orchestrate the cellular responses to hypoxia. It is a het...

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Détails bibliographiques
Auteurs principaux: Kaur, Balveen, Khwaja, Fatima W., Severson, Eric A., Matheny, Shannon L., Brat, Daniel J., Van Meir, Erwin G.
Format: Artigo
Langue:Inglês
Publié: Duke University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871894/
https://ncbi.nlm.nih.gov/pubmed/15831232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704001115
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