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Bcl-X(L)-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides
Protein-protein interactions have key importance in various biological processes and modulation of particular protein-protein interactions has been shown to have therapeutic effects. However, disrupting or modulating protein-protein interactions with low-molecular-weight compounds is extremely diffi...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574679/ https://ncbi.nlm.nih.gov/pubmed/18811158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802683u |
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