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Bcl-X(L)-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides

Protein-protein interactions have key importance in various biological processes and modulation of particular protein-protein interactions has been shown to have therapeutic effects. However, disrupting or modulating protein-protein interactions with low-molecular-weight compounds is extremely diffi...

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Detalhes bibliográficos
Main Authors: Hu, Xiangdong, Sun, Jiazhi, Wang, Hong-Gang, Manetsch, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574679/
https://ncbi.nlm.nih.gov/pubmed/18811158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802683u
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