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mTOR Mediates Survival Signals in Malignant Mesothelioma Grown as Tumor Fragment Spheroids
Solid tumors such as mesothelioma exhibit a stubborn resistance to apoptosis that may derive from survival pathways, such as PI3K/Akt/mTOR, that are activated in many tumors, including mesothelioma. To address the role of PI3K/Akt/mTOR, we used a novel approach to study mesothelioma ex vivo as tumor...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574528/ https://ncbi.nlm.nih.gov/pubmed/18511708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0460OC |
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