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Contribution of extracellular negatively charged residues to ATP action and zinc modulation of rat P2X(2) receptors

Two histidines are known to be essential for zinc potentiation of rat P2X(2) receptors, but the chemistry of zinc coordination would suggest that other residues also participate in this zinc binding site. There is also a second lower affinity zinc binding site in P2X(2) receptors whose constituents...

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Detalhes bibliográficos
Main Authors: Friday, Sean C., Hume, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574510/
https://ncbi.nlm.nih.gov/pubmed/18194442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05228.x
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