In Vivo Microdialysis Study of the Penetration of Daptomycin into Soft Tissues in Diabetic versus Healthy Volunteers

Daptomycin is approved for the treatment of complicated skin and soft tissue infections, including diabetic wounds of the lower extremities, at a dose of 4 mg/kg of body weight once daily. For such localized tissue infections, drug concentrations in the interstitial space are an important determinan...

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Detalles Bibliográficos
Main Authors: Kim, Aryun, Suecof, Larry A., Sutherland, Christina A., Gao, Lihong, Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Clinical Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573116/
https://ncbi.nlm.nih.gov/pubmed/18779352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00589-08
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