MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27(Kip1)

We explored the role of microRNAs (miRNAs) in acquiring resistance to tamoxifen, a drug successfully used to treat women with estrogen receptor-positive breast cancer. miRNA microarray analysis of MCF-7 cell lines that are either sensitive (parental) or resistant (4-hydroxytamoxifen-resistant (OHT(R...

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Bibliographische Detailangaben
Hauptverfasser: Miller, Tyler E., Ghoshal, Kalpana, Ramaswamy, Bhuvaneswari, Roy, Satavisha, Datta, Jharna, Shapiro, Charles L., Jacob, Samson, Majumder, Sarmila
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
RNA-Mediated Regulation and Noncoding Rnas
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573063/
https://ncbi.nlm.nih.gov/pubmed/18708351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804612200
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