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Podocyte-Specific Overexpression of the Antioxidant Metallothionein Reduces Diabetic Nephropathy

Podocytes are critical components of the selective filtration barrier of the glomerulus and are susceptible to oxidative damage. For investigation of the role of oxidative stress and podocyte damage in diabetic nephropathy, transgenic mice that overexpress the antioxidant protein metallothionein (MT...

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Autores principales: Zheng, Shirong, Carlson, Edward C., Yang, Lu, Kralik, Patricia M., Huang, Yun, Epstein, Paul N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573005/
https://ncbi.nlm.nih.gov/pubmed/18632844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007080967
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