Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes

The effect of diabetes in vivo has not been examined on isolated podocytes. To achieve this, GFP was expressed constitutively in podocytes of PGFP transgenic mice which were bred to OVE mice to produce diabetic OVE-GFP mice. Viewing GFP fluorescence, foot processes of OVE-GFP podocytes were visually...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Xu, Jianxiang, Zheng, Shirong, Kralik, Patricia M., Krishnan, Laxminarayanan, Huang, Hui, Hoying, James B., Cai, Lu, Carlson, Edward C., Tan, Yi, Epstein, Paul N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737677/
https://ncbi.nlm.nih.gov/pubmed/26884718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13057
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