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Diabetes Induced Changes in Podocyte Morphology and Gene Expression Evaluated Using GFP Transgenic Podocytes

The effect of diabetes in vivo has not been examined on isolated podocytes. To achieve this, GFP was expressed constitutively in podocytes of PGFP transgenic mice which were bred to OVE mice to produce diabetic OVE-GFP mice. Viewing GFP fluorescence, foot processes of OVE-GFP podocytes were visually...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Xu, Jianxiang, Zheng, Shirong, Kralik, Patricia M., Krishnan, Laxminarayanan, Huang, Hui, Hoying, James B., Cai, Lu, Carlson, Edward C., Tan, Yi, Epstein, Paul N.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737677/
https://ncbi.nlm.nih.gov/pubmed/26884718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.13057
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