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Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Frontotemporal dementia (FTD) is characterized by cognitive and behavioral changes and, in a significant subset of patients, Parkinsonism. Histopathologically, FTD frequently presents with tau-containing lesions, which in familial cases result from mutations in the MAPT gene encoding tau. Here we pr...

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Detalhes bibliográficos
Main Authors: Ittner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter, Götz, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572931/
https://ncbi.nlm.nih.gov/pubmed/18832465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808084105
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