A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

At the site of microbial infections, the significant influx of immune effector cells and the necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which both the pathogen and host cells must survive. Currently, whether hypoxia adaptation is an important virulence attribut...

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Detalhes bibliográficos
Main Authors: Willger, Sven D., Puttikamonkul, Srisombat, Kim, Kwang-Hyung, Burritt, James B., Grahl, Nora, Metzler, Laurel J., Barbuch, Robert, Bard, Martin, Lawrence, Christopher B., Cramer, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572145/
https://ncbi.nlm.nih.gov/pubmed/18989462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000200
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