A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

At the site of microbial infections, the significant influx of immune effector cells and the necrosis of tissue by the invading pathogen generate hypoxic microenvironments in which both the pathogen and host cells must survive. Currently, whether hypoxia adaptation is an important virulence attribut...

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Hlavní autoři: Willger, Sven D., Puttikamonkul, Srisombat, Kim, Kwang-Hyung, Burritt, James B., Grahl, Nora, Metzler, Laurel J., Barbuch, Robert, Bard, Martin, Lawrence, Christopher B., Cramer, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572145/
https://ncbi.nlm.nih.gov/pubmed/18989462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000200
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