Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

After exposure to DNA-damaging agents that block the progress of the replication fork, monoubiquitination of proliferating cell nuclear antigen (PCNA) mediates the switch from replicative to translesion synthesis DNA polymerases. We show that in human cells, PCNA is monoubiquitinated in response to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Niimi, Atsuko, Brown, Stephanie, Sabbioneda, Simone, Kannouche, Patricia L., Scott, Andrew, Yasui, Akira, Green, Catherine M., Lehmann, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571029/
https://ncbi.nlm.nih.gov/pubmed/18845679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802727105
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge