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Effect of Proliferating Cell Nuclear Antigen Ubiquitination and Chromatin Structure on the Dynamic Properties of the Y-family DNA Polymerases

Y-family DNA polymerases carry out translesion synthesis past damaged DNA. DNA polymerases (pol) η and ι are usually uniformly distributed through the nucleus but accumulate in replication foci during S phase. DNA-damaging treatments result in an increase in S phase cells containing polymerase foci....

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Detalhes bibliográficos
Main Authors: Sabbioneda, Simone, Gourdin, Audrey M., Green, Catherine M., Zotter, Angelika, Giglia-Mari, Giuseppina, Houtsmuller, Adriaan, Vermeulen, Wim, Lehmann, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592664/
https://ncbi.nlm.nih.gov/pubmed/18799611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0724
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