Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

We have performed a genome-wide analysis of copy number changes in breast and colorectal tumors using approaches that can reliably detect homozygous deletions and amplifications. We found that the number of genes altered by major copy number changes, deletion of all copies or amplification to at lea...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Leary, Rebecca J., Lin, Jimmy C., Cummins, Jordan, Boca, Simina, Wood, Laura D., Parsons, D. Williams, Jones, Siân, Sjöblom, Tobias, Park, Ben-Ho, Parsons, Ramon, Willis, Joseph, Dawson, Dawn, Willson, James K. V., Nikolskaya, Tatiana, Nikolsky, Yuri, Kopelovich, Levy, Papadopoulos, Nick, Pennacchio, Len A., Wang, Tian-Li, Markowitz, Sanford D., Parmigiani, Giovanni, Kinzler, Kenneth W., Vogelstein, Bert, Velculescu, Victor E.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2008
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2571022/
https://ncbi.nlm.nih.gov/pubmed/18852474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808041105
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