Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress

OBJECTIVE—Endoplasmic reticulum stress increases macrophage apoptosis, contributing to the complications of atherosclerosis. Insulin-resistant macrophages are more susceptible to endoplasmic reticulum stress–associated apoptosis probably contributing to macrophage death and necrotic core formation i...

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Detalhes bibliográficos
Main Authors: Senokuchi, Takafumi, Liang, Chien-Ping, Seimon, Tracie A., Han, Seongah, Matsumoto, Michihiro, Banks, Alexander S., Paik, Ji-Hye, DePinho, Ronald A., Accili, Domenico, Tabas, Ira, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570393/
https://ncbi.nlm.nih.gov/pubmed/18728232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0520
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