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Formation of Purine–Purine Mispairs by Sulfolobus solfataricus DNA Polymerase IV

DNA damage that stalls replicative polymerases can be bypassed with the Y-family polymerases. These polymerases have more open active sites that can accommodate modified nucleotides. The lack of protein–DNA interactions that select for Watson–Crick base pairs correlate with the lowered fidelity of r...

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Bibliografiske detaljer
Main Authors: DeCarlo, Lindsey, Gowda, A. S. Prakasha, Suo, Zucai, Spratt, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570044/
https://ncbi.nlm.nih.gov/pubmed/18616289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800820m
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