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Formation of Purine–Purine Mispairs by Sulfolobus solfataricus DNA Polymerase IV

DNA damage that stalls replicative polymerases can be bypassed with the Y-family polymerases. These polymerases have more open active sites that can accommodate modified nucleotides. The lack of protein–DNA interactions that select for Watson–Crick base pairs correlate with the lowered fidelity of r...

詳細記述

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書誌詳細
主要な著者: DeCarlo, Lindsey, Gowda, A. S. Prakasha, Suo, Zucai, Spratt, Thomas E.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570044/
https://ncbi.nlm.nih.gov/pubmed/18616289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800820m
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