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Randomized Phase III ClinicalTrial Designs forTargeted Agents

PURPOSE: Cancer therapies with mechanisms of action which are very different from the more conventional chemotherapies are now being developed. In this article, we investigate the performance of several phase III clinical trial designs, both for testing the overall efficacy of a targeted agent and f...

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Autori principali: Hoering, Antje, LeBlanc, Mike, Crowley, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569946/
https://ncbi.nlm.nih.gov/pubmed/18628448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0288
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