Unaltered repopulation properties of mouse hematopoietic stem cells transduced with lentiviral vectors

Recent studies of retroviral-mediated gene transfer have shown that retroviral integrations themselves may trigger nonmalignant clonal expansion of hematopoietic stem cells (HSCs) in transplant recipients. These observations suggested that previous conclusions of HSC dynamics based on gamma-retrovir...

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Autores principales: Gonzalez-Murillo, Africa, Lozano, M. Luz, Montini, Eugenio, Bueren, Juan A., Guenechea, Guillermo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2008
Materias:
Gene Therapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569169/
https://ncbi.nlm.nih.gov/pubmed/18684860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-142661
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