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Inhibition of poliovirus polymerase by guanidine in vitro.

Extracts from poliovirus-infected HeLa cells synthesized 35s viral RNA, replicative intermediate, and double-stranded RNA in vitro. Guanidine inhibited the synthesis of all three species of RNA; production of 35s RNA was most sensitive to the inhibitor. Pulse-chase experiments with [3H]UTP indicated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Tershak, D R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1982
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC256753/
https://ncbi.nlm.nih.gov/pubmed/6283124
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