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Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
The potassium channel Kv1.3 has recently been located to the inner mitochondrial membrane of lymphocytes. Here, we show that mouse and human cells that are genetically deficient in either Kv1.3 or transfected with siRNA to suppress Kv1.3-expression resisted apoptosis induced by several stimuli, incl...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567458/ https://ncbi.nlm.nih.gov/pubmed/18818304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804236105 |
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