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Backtracking on the folding landscape of the β-trefoil protein interleukin-1β?
Interleukin-1β (IL-1β) is a cytokine within the β-trefoil family. Our data indicate that the folding/unfolding routes are geometrically frustrated. Follow-up theoretical studies predicted backtracking events that could contribute to the broad transition barrier and the experimentally observed long-l...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567455/ https://ncbi.nlm.nih.gov/pubmed/18806223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807812105 |
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