LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein

LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate that LIS1 suppresses the motility of cytoplasmic dynein on microtubules (MTs), whereas NDEL1 releases t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Yamada, Masami, Toba, Shiori, Yoshida, Yuko, Haratani, Koji, Mori, Daisuke, Yano, Yoshihisa, Mimori-Kiyosue, Yuko, Nakamura, Takeshi, Itoh, Kyoko, Fushiki, Shinji, Setou, Mitsutoshi, Wynshaw-Boris, Anthony, Torisawa, Takayuki, Toyoshima, Yoko Y, Hirotsune, Shinji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567412/
https://ncbi.nlm.nih.gov/pubmed/18784752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.182
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk