טוען...
Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation
The glycosylphosphatidylinositol (GPI)-anchored proteoglycan Cripto binds Nodal and its type I receptor Alk4 to activate Smad2,3 transcription factors, but a role during Nodal precursor processing has not been described. We show that Cripto also binds the proprotein convertases Furin and PACE4 and l...
שמור ב:
| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567404/ https://ncbi.nlm.nih.gov/pubmed/18772886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.174 |
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