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The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity
Single-nucleotide polymorphisms (SNPs) in the human ether-a-go-go-related gene 1, hERG1, are associated with cardiac arrhythmias. The Kv11.1 channels encoded by hERG1 are also essential for rhythmic excitability of the pituitary, where they are regulated by thyroid hormone through a signal transduct...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567201/ https://ncbi.nlm.nih.gov/pubmed/18791070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802250105 |
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