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Computational Studies of the Farnesyltransferase Ternary Complex Part I: Substrate Binding

Farnesyltransferase (FTase) catalyzes the transfer of farnesyl from farnesyldiphosphate (FPP) to cysteine residues at or near the C-terminal of protein acceptors with a CaaX motif (a, aliphatic; X, Met). Farnesylation is a critical modification to many switch proteins involved in extracellular signa...

詳細記述

保存先:
書誌詳細
主要な著者: Cui, Guanglei, Wang, Bing, Merz, Kenneth M.
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566548/
https://ncbi.nlm.nih.gov/pubmed/16342942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051020m
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