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Computational Studies of the Farnesyltransferase Ternary Complex Part I: Substrate Binding
Farnesyltransferase (FTase) catalyzes the transfer of farnesyl from farnesyldiphosphate (FPP) to cysteine residues at or near the C-terminal of protein acceptors with a CaaX motif (a, aliphatic; X, Met). Farnesylation is a critical modification to many switch proteins involved in extracellular signa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566548/ https://ncbi.nlm.nih.gov/pubmed/16342942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051020m |
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